Where to inject tirzepatide
Where to inject Tirzepatide under the skin, ways to rotate spots and what any label says.
- the usual places beneath the skin
- Upper arm, thigh or belly
- clear of the belly button
- a distance of 2 inches
- a fresh spot for each dose
- Rotate
Where to inject Tirzepatide
The Zepbound label directs you to use the belly or thigh under the skin. Another person can give it in the back of the upper arm. For every dose, use a different spot inside your chosen area.
- Belly: at least 2 inches from the belly button, at a spot you can pinch.
- Front or outer thigh: between the knee and hip, in the middle area.
- The back of the upper arm is easier when another person gives the injection.
Using a vial for a tirzepatide injection
- Clean your hands with soap and water, then use an alcohol swab on the spot.
- Draw the dose to the right line; if you're unsure about the units, check them with the calculator.
- Pinch a fold of skin, insert the needle using the angle your prescriber showed you, then press the plunger slowly.
- Take the needle out of your skin, press the spot lightly with a cotton ball and place the syringe in a sharps container.
Changing where you inject
Each time, use a spot at least an inch from the one you used last. Rotating spots lowers the chance of lumps or pits beneath your skin. Do not use skin that is sore, bruised, red or has scars.
For more about technique, see subq injection and the MedlinePlus guide on shots under the skin.
Questions people often ask
Where I inject Tirzepatide, does it make a difference?
The usual choices under the skin are the belly, thigh and upper arm. Choose one area and rotate spots inside it, unless your label or prescriber gives different instructions.
Is pinching the skin the right choice?
Check with your prescriber; the labels we list leave that choice to your prescriber. Many people use short insulin needles and pinch a fold of skin.